http://www.medscape.com/viewarticle/768781

ICDShocksExplainPartofDeclineinVFCardiacArrestsinDutchStudy荷兰的一项研究显示,ICD可减少VF所致心脏骤停Cardiacarrestsfromventricularfibrillation(VF)innorthernHollanddecreasedfrom63%ofallarreststo47%ofallarrestsoverthepastdecade,andathirdofthisdeclinecanbeattributedtosuccessfulshocksfromimplantablecardioverterdefibrillators(ICDs),researchersreport[1].
研究人员报告称,在过去十年中,荷兰北部的室颤(VF)所致的心跳骤停从占所有心脏骤停的63%下降到47%,下降的三分之一可归功于植入型心律转复除颤器(ICDs)的应用[1].
Thestudy,withseniorauthorDrRudolfWKoster(LeidenUniversityMedicalCenter,theNetherlands),ispublishedonlineAugust6,2012inCirculation.
本研究在线发表在2012年8月6日的《循环》杂志上.
该研究的主要作者是RudolfW博士(荷兰莱顿大学医学中心).
"Whiletheincidenceofout-of-hospital[VF-relatedcardiacarrest]hasbeendeclininginmanycountriesforadecade,ithasnotbeenpossiblepreviouslytodeterminetowhatextentthiswasduetotherapyforcoronaryheartdisease,revascularization,ICDs,orotherfactors,"DrNAMarkEstes(TuftsUniversitySchoolofMedicine,Boston,MA),whowasnotinvolvedinthestudy,toldheartwireinanemail.
NAMarkEstes博士(他并未参与该项临床研究)说,"虽然在过去十年内,许多国家的院外事件(心室颤动引起的心脏骤停)发生率明显下降,但之前一直不太明白究竟是什么原因导致其发生率下降,是因为冠状动脉心脏病还是心脏血管的重建、植入型心律转复除颤器(ICDs)的应用还是其他原因.
"Thisnovelstudyusedrobustmethodology,headded,andshowedthat"appropriateuseofICDscontributestoadeclineinthefrequencyof[out-of-hospitalcardiacarrests]fromVFandtherebysaveslives.
"Theteamalsofoundanincreaseinnon–VF-relatedout-of-hospitalcardiacarrests,and"thereasonsforthisincreaseareunknownbutmeritinvestigation,"Estesnoted.
该项新研究采用了非常好的临床方法,研究发现,正确使用植入型心律转复除颤器(ICDs)可使心室颤动引起的院外心脏骤停发病率下降,因而挽救了生命.
同时该研究小组也发现非心室颤动性心脏骤停发病率升高,目前增加的原因还尚未知晓.

ARRESTingResearch进一步研究Accordingtoseveralstudies,overa15-yearperiod,theproportionofout-of-hospitalcardiacarreststhatareVF-relatedhasdeclined,onaverage,from54%to38%intheUSandEurope.
几项研究显示,美国和欧洲各国15年间院外心室颤动性心脏骤停的比例从原来的54%下降到至38%.
ToconfirmthisdeclineandtocalculatetheextenttowhichthismightbeexplainedbytheuseofICDs,theteamanalyzeddatafromtheAmsterdamResuscitationStudies(ARREST)prospectivedatabaseofallresuscitationeffortsinHolland.
为了进一步确认上述结果并计算使用植入型心律转复除颤器(ICDs)在其中发挥的作用,该研究小组分析了在荷兰进行的前瞻性复苏数据库ARREST临床数据.
TheycomparedtheincidenceofVFcardiacarrestinNorthHolland(whichincludesAmsterdam)from1995to1997,whenICDimplantationwasrare,vsfrom2005to2008,whenICDusewascommon.
他们对1995-1997年间(此期间植入型心律转复除颤器(ICDs)非常的少)和2005-2008年期间(该期间植入型心律转复除颤器(ICDs)应用普遍)室颤性心脏骤停发生率进行了比较.