Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
hostwinds怎么样?2021年7月最新 hostwinds 优惠码整理,Hostwinds 优惠套餐整理,Hostwinds 西雅图机房直连线路 VPS 推荐,目前最低仅需 $4.99 月付,并且可以免费更换 IP 地址。本文分享整理一下最新的 Hostwinds 优惠套餐,包括托管型 VPS、无托管型 VPS、Linux VPS、Windows VPS 等多种套餐。目前 Hostwinds...
racknerd怎么样?racknerd商家最近促销三款美国便宜vps,最低只需要9.49美元,可以选择美国圣何塞、西雅图、纽约和芝加哥机房。RackNerd是一家成立于2019年的美国高性价比服务器商家,主要从事美国和荷兰数据中心的便宜vps、独立服务器销售!支持中文工单、支持支付宝和微信以及PayPal付款购买!点击直达:racknerd官方网站INTEL系列可选机房:加利福尼亚州圣何塞、芝加...
在上个月的时候也有记录到 NameCheap 域名注册商有发布域名转入促销活动的,那时候我也有帮助自己和公司的客户通过域名转入到NC服务商这样可以实现省钱续费的目的。上个月续费转入的时候是选择9月和10月份到期的域名,这不还有几个域名年底到期的,正好看到NameCheap商家再次发布转入优惠,所以打算把剩下的还有几个看看一并转入进来。活动截止到9月20日,如果我们需要转入域名的话可以准备起来。 N...