identity77vcd.com

Indexabnonnalvision42achalasia18adrenergicdrug177adverseevent42,76,176adverseevents,decreaseof176age-associatedchangesinmalesexualresponse103ageingmale90alcoholuse108allostericsite,POE523alprostadil53amantadine111,112amlodipine157amygdala68ancientmysteriousrules,chineseperception192antidepressant102,108,111antidote111antihypertensivemedication35,157,158aphrodisiacs189apomorphine77,106,107apoptosis52arousal117,118,120-124arrhythmia153,156arrhythmia,POE5inhibitors156ASIAscores72audio-visualsexualstimulation(AVSS)73Augustine188autonomicdysreflexia76Barrington'snucleus68BDI110benignprostatichyperplasia(BPH)44,109,110biochemicalpotency23bladderdysfunction74a-blocker41,147~-blocker41195bulbocavernousreflex(BCR)72,73bupropion111buspirone111,112cAMP15,163cardioprotectiveeffectsofPOE5inhibitors159cardiovasculardisease108,129,135,151-159cardiovasculardisease,patientcounceling154cardiovasculardisease,treatmentofEOwithPOE5inhibitors155,156cardiovasculardiseaseandcontraindications,POE5inhibitor157cardiovasculardrugsandPOE5inhibitors155-158cardiovasculardrugsandsildenafil155,156cardiovasculareffect26cardiovascularmortalityandPOE5inhibitors158,159cardiovascularriskandsexualactivity152-154cardiovascularsafety135catalyticdomain,POE521catecholamines102Caverject107cavernousnerve51,57cavernousnerveinterpositiongrafting57cavernousnervereconstruction57centralnervoussystem68CES-O109196cGMP15,21,36,54,103,106,129,156,163childlessness185Chineseperception192christian-humanisticbelief188,189chronicdialysis91chronicheartfailure131chronicobstructivelungdisease166chronicpelvicpainsyndrome(CPPS)184chronicstablecoronaryarterydisease152chronictreatmentwithPDE5inhibitors159chronicledevice153cimetidine106classicalliberalism192clinicalinterview110clomipramine(CMI)105,106CMItherapy106CologneMaleSurvey170combinationtherapy,treatmentofnon-responders172co-morbidity,cardiovasculardiseases151,152co-morbidity,modelsof108congestiveheartfailure44,152,153contraception188coronaryarterydilation41coronaryarterydisease133,153,159coronaryheartdisease152,155coronaryheartdisease,PDE5inhibitors155cross-talk19culture,decline190cyclicadenosinemonophosphate(cAMP)15,163cyclicguanosinemonophosphate(cGMP)15,21,36,54,103,106,129,156,163cyclicGMP-bindingsite21cyclicGMP-specificphosphodiesterasetype5(PDE5)106CYP2C9158CYP3A4158cyproheptadine111cytochromeP450system158Indexdefectiveregionalvenousflow170depression39,70,71,75,92,108-112depressionandsexualdysfunctioninmen108-112DHE175,180DHE,dualdrugapproach180diabetesmellitus72,90,134diabeticpatient38diaspora192Dionysuscult189dizziness42dopamine68,102dopaminergicdrugs102dosetitration42drugdevelopment5-7druginteraction143dyspepsia42dysphoria109dysreflexia76endothelialdysfunction131Enzyklikahumanaevitae190EpidemiologicStudiesDepressionScale(CES-D)109epidemiology170Epikur189erectilecapacity188ED,psychosocialimplications84EDetiology,mixed38EDetiology,organic38EDetiology,psychogenic38,39erythromycin106estrogen119,122-124excretion148exercisetreadmilltesting(ETI)152failurerate,elderlymen171fanatism193femalesexualdysfunction44IndexFrenchRevolution191frenulumsqueezeprocedure105GinkgobilobaIIIglobalefficacyassessment37glutamate68Goethe187granisetron111Greekunderstandingofmen191guanylcyclase19guanylatecyclase163guiltfeelings85HamiltonRatingScaleforDepression(HAM-D)110headache42HealthProfessionalsFollow-upStudy151heartfailure44,131,152,153,155,159heartfailure,PDE5inhibitors155hermatospermia184highercivilization188hippocampus68Hippocrates189HIVproteaseinhibitor157,158Huxley188hypertension38,157-159hypertensivepatient157hypoactivesexualdesiredisorder(HSDD)103-105hypogastricnerve(HGN)68,69hypogonadism108hypotension156,157hypothalamus68hypoxia164ICHGuidelineonClinicalSafety176identityofdrugs173iloprost159immunophilin59ImperialRome189infertility,male185inflammatoryboweldisease93197integratederectionstatus(IES)172InternationalIndexofErectileFunction(lIEF)50,72interstitiallungdisease165,166intracavernosalinjectiontherapy54,107ischemicheartdisease42JohnsHopkinsSexualBehaviorsConsultingUnit109Judaism189,190kidneytransplantrecipient91KingDavid189KingSalomon189libido184,187libidoloss184locuscoeruleus68lowermotoneuronlesion(LMN)69lowerurinarytractsymptoms44lumbosacralmotornuclei105,111maleerectiledysfunction(MED)15,17,20mammaliansexuality187marriage190MassachusettsMaleAgingStudy(MMAS)109,151,152,170maximumserumconcentration43majordepressivedisorder(MDD)108,109,111,112measurementofmaleerectileresponse108medicalriskfactor171medication,discontinuation42medullaoblongata68menopause117,120,121,123,124Mephistopheles187mesolimbicsystem71midbrain68mirtazepine111monoamineoxidaseinhibitor(MAOI)107,111198monovalentdrugapproach178mood109,112MultinationalSurveyoftheAgingMale(MSAM-7)170multipleregulatorymechanism171multiplesclerosis(MS)39,70,72,76multiplesystematrophy(MSA)91myocardialinfarction(MI)42,152myosinlightchainkinase(MLCK)103myosinlightchainphosphatase(MLCP)103nebivolol147nefazodone111nervesparing50nervesparingradicalprostatectomy50nervierigentes69nervoussystem102neuroplasticity69neuroprotection58neurotrophicfactors59neurovascularbundle51neurovascularphysiologyoferectilefunction103newtargets,treatmentofEO172NewTestament188nicorandil147nitrate106,144,156,157nitricoxide(NO)19,20,36,54,102,103,106,111,129,156,157,163,177NO-donator106,156,157NO-synthase36,163nitroglycerin26nitrovasodilator20,26nocturnalpeniletumescence(NPT)73,108nocturnalpeniletumescenceandrigiditytesting(NPTR)73non-kosherresidues192non-responder170,172norepinephrine(NE)68,102Indexnucleusparagigantocellularis68OldTestament189onsetafteringestion,sildenafil43opennon-blindedstudy173organicnitrate156,157oxytocin68PAH163,164parapyrarnidalreticularformation68paraventricularnucleus68Parkinson'sdisease(PO)70,72,76,91pathologicalcavernosogram177patientcouncelingregardingsexualactivityandcardiovasculardisease154pause-squeezetechnique105penileconstrictiondevice75penilecorpuscavernosum26peniledeformity107penilefibrosis183penileintracavernosalinjection110penileprosthesis77,107penileself-injectiontherapy107peniletumescence108penilevascularsmoothmuscle20penilevasculature20penilevibratorstimulation75pervasiveanhedonia111Peyronie'sdisease107,183phalluscult188pharmacokineticproperties,sildenafil27pharmacotesting73POE5inhibitor,abuseof179POE5inhibitorsandcardiovasculardiseases154-159POE6family25PKG21plateletaggregation27pons68post-ejaculatorypain184postoperativeEO,treatment53post-warsituation191Indexprematureejaculation(PE)104-106,184priapism107prostaglandin103,171prostaglandinEl77prostatecancertherapy92prostatectomy39,49,50,93prostatitis,chronic184prostatitis,definitionsforthedifferenttypes184prostatitis,nonbacterial184psychobiology,sexualfunction102psychogenicerection69,73-75psychosexualtherapy75psychosocialdistress108psychosocialhealth95psychostimulant111psychotropicdrugs94,105,110-112pudendalnerve72pudendalsomatosensoryevokedpotential74pulmonaryarterialhypertension(PAH)18,44,135,163,164QRScomplex41QTdynamics156qualityoflife(QoL)43,83,85,87,95QoL,assessmentinstrumentforerectilefunction87qualityofpartnership(QoP)83,85,87,95QoP,assessmentinstrumentforerectilefunction87radicalprostatectomy40,49,93raphemagnus68raphepallidus68Raynaud'ssyndrome18,159rectalcancer,treatment93reflexogenicerection68,69,73-75retrogradeejaculation68rhinitis42ritonavir158199rococo191RomanEmperors189sacrosanctbordersofmen192selectiveserotoninreuptakeinhibitor39self-esteem,lossof95self-injectiontechnique107Seneca189serotonergicmedication111serotonin39,68,102,111serumhalflife43sexsteroid102sexualactivitywithheartdisease152-154sexualdysfunction69,70,103,109,110sexualdysfunction,classification103sexualdysfunction,impactonmood109,110sexualencounterprofile37sexualfantasy104sexualfunction101,102,108,109,117,120-123sexualfunction,age101,102sexualfunction,depression108,109sexualfunction,monoamines102sexualfunction,phasesof101sexualfunction,psychobiology102sexualhistory72sexualresponsecycle101,102sexualsatisfaction83sildenafil,cost-effectiveness96,97sildenafil,cost-utility97sildenafil,efficacy36sildenafil,publicacceptance96sildenafil,publicopinion96sildenafil,safety36sildenafilcitrate(Viagra)1-5,7,8,17,18,20,25,35,3~117,122sildenafiltreatment,negativeeffects94Sinocentrictopos192smoking39200socialperturbances193Socrates189SodomandGomorrah189specificefficacyvariables174spermaticvein177spermatozoadysfunction177sphincterextemusurethrae177sphincterintemusurethrae177sphinctericdysfunction70spinalcordinjury39,69,76,90spousalsatisfaction40SSRI105,111,112SSRI-associatedsexualdysfunction112SSRItreatment111stablecoronaryarterydisease153stroke18structuredclinicalinterview110Suctonius189suralnervegrafting57sympatheticnervoussystem68,69sympatheticskinresponse(SSR)74sympathicomimeticcompound172systemicbloodpressure27tachyphylaxis43tadalafil54,77,106,137,143,159testosterone104,105,120,123,124tricyclicantidepressants(TCAs)111two-samplet-test175TypeIdiabetes38TypeIIdiabetes159uppermotomeuronlesion(UMN)69uremia91urodynamics74vacuumconstrictiondevice(VCD)therapy107valvulardisease153,154vardenafil17,54,77,106,107,133,159varicocelevein177vascularendothelium130vascularsmoothmuscle19,129vasoactiveintestinalpolypeptide(VIP)103Indexvasodilationsymptoms42veno-occlusivedysfunction183Viagra1-5,7,8,17,18,20,25,35,36,117,122Virgil189virility,male188war191wellbeing83yohimbineIIIWherequalitymeetsscientificresearch.
.
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BirkhiiuserGuglietta,A.
,GrupoFerrerInternacional,Barcelona,Spain(Ed.
)PharmacotherapyofGastrointestinalInflammation2003.
156pages.
HardcoverISBN3-7643-6910-8PIR-ProgressinInflammationResearchInrecentyears,theareaofpharmacotherapyofGIinflammationhaswitnessedimportantprogresseswithnewdrugsandtherapeuticapproachesbeingintroduced.
Thevolumereviewsthepharmacotherapyofselectedgastrointestinalinflammatoryconditionschosenonthebasisoftheirclinicalimportanceandtheareaswhereimportantandexcitingprogresseshavebeenmaderecently.
BesidesdiscussingcurrentpharmacotherapytotreatthemostimportantGIinflammationconditions,thebookalsoindicatespossiblefuturetherapeuticavenueslikelytobecomeavailableinafewyears.
Thebookisofinteresttovarioussectorsofthescientificcommunityrangingfromclinicianstopharmacologistsandfrombiochemiststomicrobiologistswhowillfinditanusefultoolfortheirclinicalpracticeandresearchactivity.
Fromthecontents:MarcoRomanoandAntonioCuomo:PharmacotherapyofHelicobacterpylori-associatedgastritisMarijaVeljaca:PharmacotherapyofinflammatoryBowelDisease:noveltherapeuticapproachesFlaviaLirussiandBeniaminoZalunardo:CurrentandfuturetherapyofchronichepatitisE.
Bergogne-Berezin:TreatmentandpreventionofantibioticassociatedcolitisForordersoriginatingfromallovertheworldexceptUSAandCanada:BirkhauserVerlagAGdoSpringerGmbH&CoHaberstrasse7D·69126HeidelbergFax:+49/622113454229e-mail:birkhauser@springer.
dehttp://www.
birkhauser.
chForordersoriginatingintheUSAandCanada:Birkhiiuser333MeadowlandParkwayUSA-SecaucusNJ07094-2491Fax:+12013484505e-mail:orders@birkhauser.
comWherequalitymeetsscientificresearch.
.
.
BirkhiiuserPatret,M.
IvanRyn,J.
tbothBoehringerIngelheim,Biberach,Germany(Eds.
)COX-2Inhibitors2004.
260pages.
HardcoverISBN3-7643-6901-9MDT-MilestonesinDrugTherapyTheoriginaltheoryofinducibleCOX-2andconstitutiveCOX-1iscontinuallybeingupdated.
COX-2isnotonlyinducedduringinflammationbutisconstitutivelyexpressedinvarioustissueswhereitisnecessaryforphysiologicalfunctions.
Ithas,however,beenconcluSivelydemonstratedthatCOX-linhibi-torsareimportantdrugswithanalgesicandanti-inflammatoryactivity,andthishasconfirmedtheimportanceofCOX-2ininflammation.
ThediscoveryofCOX-2.
itschemicalbasisandthedevelop-mentofinhibitorydrugsarereviewedinthisbook.
SincealargeamountofclinicalexperiencewithCOX-2inhibitorsisnowavailable,theimplicationsofthesedevelopmentsforfuturetherapyarealsocovered.
AdditionalinformationontherolesofCOX-'andCOX-2inmucosalprotedionandulcerhealingalsoallowabetterassessmentofthelevelofimpro-vementachievedbyCOX-2inhibitors.
Thiscomprehensivemonographisofinteresttocliniciansandresearchersinacademiaandindustryaswellasforadvancedstudentsinthefield.
Fromthecontents:ReginaM.
BottingandJackH.
Botting:ThediscoveryofCOX-2LawrenceJ.
MarnettandAmie5.
Kalgutkar:StruduraldiversityofselediveCOX-2inhibitorsGuenterTrummfitz,JoannevanRynandTimothyD.
Warner:ThemolecularandbiologicalbasisforCOX-2selectivityK.
D.
Rainsford:PharmacologyandtoxicologyofCOX-2inhibitorsFororde~originatingfromallovertheworldexceptUSAandCanada:8irkhauserVerlagAGdoSpringerAuslieferungs-Gesells(SAG)CustomerServiceHaberstrasse7,0·69126HeidelbergTel.
:+49f6221f34S0Fax:+49f6221f3454229e-mail:orders@birkhauser.
chFororde~originatingintheU5AandCanada:8irkhauser333MeadowlandParkwayUSA-SeGiucusNJ07094-2491Fax:+\2013484505e-mail:orde~@birkhauser.
com