dataavmoo.com
avmoo.com 时间:2021-03-20 阅读:()
Biologicallypotentdioxomolybdenum(VI)complexeswithnitrogen-sulfurandnitrogen-oxygendonarligands:Synthesis,characterisationandantimicrobialactivityINTRODUCTIONMolybdenumisanimportanttransitionelement,whichhasamajorroleastraceelementsandisanin-dispensableconstituentofenzymesthatareinvolvedinthefunctionofnitrogenfixingnitrogenase[1].
Alargenum-berofstableandaccessibleoxidationstatesandcoor-dinationnumberrendermolybdenumtobeaversatiletransitionelement.
Molybdenumistheonlyelementinthesecondandthirdtransitionserieswhichplaysmajorroleastraceelementinenzymes.
Thepresenceofcis-dioxymolybdenumcation[MoO2]+2intheoxidizedformofcertainmolybdoenzymeshasrecentlygeneratedtre-AshuChaudhary1*,R.
V.
Singh21DepartmentofChemistry,BanasthaliUniversity,Rajasthan,(INDIA)2DepartmentofChemistry,UniversityofRajasthan,Jaipur-302004,(INDIA)E-mail:ashuchaudhary21@gmail.
comReceived:24thJuly,2008;Accepted:29thJuly,2008mendousinterest[2].
Thecis-[MoO2]+2centredominatesthechemistryofdomolybdenum(VI)complexes[3]andparticipatesinmanyoxygenatomtransferreactions[4-6].
Schiffbasesareanimportantclassofligandsinco-ordinationchemistryandhavemanyapplications[7]invariousfields.
ThechemistryofSchiffbasecomplexescontinuestoattractmanyresearchers[8,9]becauseoftheirwideapplicationsinfoodindustry,dyeindustry,ana-lyticalchemistry,catalysis,antimicrobialactivity,agrochemicalactivity[10]andpharmacologicalapplications[11].
TheSchiffbaseshavebeenfoundtobeactiveagainstdifferenttypesofbacteriaandviruses.
IthasnowbeenobservedthatsomeoftheseshowincreasedKEYWORDSDioxomolybdenum(VI)complexes;Spectralstudies;Schiffbase;Antimicrobialstudies.
ABSTRACTMolybdenum(VI)complexesof3,4,5-trimethoxybenzaldehydethiosemicarbazone(TBTSCZH),3,4,5-trimethoxybenzaldehydesemicarbazone(TBSCZH),3,4,5-trimethoxy-benzaldehydebenzothiazoline(TBBZTH)and3,4,5-trimethoxybenzaldehyde-S-benzyldithiocarbazate(TBDTCZH)havebeensynthesizedandcharacterizedbyphysico-chemicalandspectroscopicstudies.
ThecomplexesMoO2(L)2(whereLrepresentedthedeprotonatedformoftheligands),wereformedbythereactionsbetweendioxobis(2,4-pentanedionato-O,O')molybdenum(VI)andtheligandsTBTSCZH,TBSCZH,TBBZTHandTBDTCZHbyusingbothtechniques(thermalandmicro-wave).
Thestructuralfeaturesofthesemolybdenumcomplexeswereex-ploredbyIR,1HNMR,13CNMRandmolecularweightdeterminations.
Anoctahedralarrangementofligandsaroundthecentralmolybdenumatomisproposed.
Allthefourligandsandtheircomplexeshavebeenscreenedfortheirbiologicalactivityonseveralpathogenicfungiandbacteriaandthedatashowgoodactivityofthesecomplexesandligands.
2008TradeScienceInc.
-INDIAFullPaperICAIJ,3(3),2008[188-192]AnIndianJournalTradeScienceInc.
Volume3Issue3September2008InorganicCHEMISTRYAshuChaudharyandR.
V.
Singh189FullPaperICAIJ,3(3)September2008InorganicCHEMISTRYInorganicCHEMISTRYAnIndianJournalactivitywhenadministeredintheformofazomethinemetalcomplexes[12].
Inviewoftheimportanceofthedioxomolybdenum(VI)complexes,wehavesynthesizedandcharacterizedsomenewcomplexesofthesaidpo-tentialbidentateligands.
EXPERIMENTALAllthechemicalsandsolventsusedweredriedandpurifiedbythestandardmethods.
Dioxobis(2,4-pentanedionato)molybdenum(VI)waspreparedac-cordingtotheliteraturemethod[13].
PreparationoftheLigandsThedifferentrouteswereemployedforthesynthe-sisoftheligands.
Theseare-1.
MicrowaveassistedsynthesisFormicrowaveassistedsynthesisoftheligandsTBTSCZH,TBSCZH,TBBZTHandTBDTCZHthethiosemicarbazide,semicarbazidehydrochloride,2-aminothiophenolandS-benzyldihiocarbazatewerere-actedwith3,4,5-trimethoxybenzaldehydeinethanolicmedia,usingaconventionalmicrowaveoven,wheretheconsumptionofethanolassolventisverylittle(2-3ml).
Thereactionswerecompletedinashortperiod(4-8minutes).
ThecompletionofthereactionischeckedbyTLC.
2.
ConventionalheatingsynthesisForthecomparisonpurpose,aboveligandswerealsosynthesizedbythethermalmethod.
Forthistheweighedamountsof3,4,5-trimethoxybenzaldehydeandthiosemicarbazide,semicarbazidehydrochlorideand2-aminothiophenolandS-benzyldihiocarbazateweremixedtogetherin100mlethanolin250mlbeaker.
Thecontentswererefluxedfor4-16hrs.
onanoilbath.
Thesolidproductswereprecipitated.
Theseweredriedinvacuumandrecrystallizedfromthesamesolvent.
AcomparisonbetweenthermalmethodandmicrowavemethodhasbeengiveninTABLE1.
Theligandsusedare:Preparationofthecomplexes1.
MicrowaveAssistedMethod:Inmicrowaveas-sistedsynthesisthereactionsofdioxobis(2,4-pentanedionato-O,O')molybdenum(VI)withtheligands(TBTSCZH,TBSCZH,TBBZTHandTBDTCZH)werecarriedoutin1:2molarratios,using2-3mlofdrymethanolasasolventusingmi-crowaveoven.
Theproductswererecoveredfromthemicrowaveovenanddriedunderreducedpres-sure.
Theresultingproductswererepeatedlywashedwithdrycyclohexaneandthenfinallydriedat40-60o/0.
5mmfor3-4hours.
2.
ConventionalHeatingMethod:Thesemolybdenum(VI)complexeswerealsosynthesizedbythether-malmethod.
Inthethermalmethodinsteadof4-7minutesreactionswerecompletedin14-16hoursandyieldofproductswerealsolesserthanobtainedbythemicrowaveassistedsynthesis(TABLE1).
RESUTLSANDDISCUSSIONThereactionsofthedioxobis(2,4-pentanedionato-O,O')molybdenum(VI)withthesaidmonofunctionalHCOCH3OCH3OCH3NNHCSNH2HCOCH3OCH3OCH3NNCSHNH2(TBTSCZH)HCOCH3OCH3OCH3NNCOHNH2HCOCH3OCH3OCH3NNHCONH2(TBSCZH)HCOCH3OCH3OCH3NHSHCOCH3OCH3OCH3NHSHCOCH3OCH3OCH3NNHCSSCH2C6H5HCOCH3OCH3OCH3NNCSHSCH2C6H5(TBBZTH)(TBDTCZH).
190Biologicallypotentdioxomolybdenum(VI)complexesFullPaperICAIJ,3(3)September2008AshuChaudharyandR.
V.
Singh191FullPaperICAIJ,3(3)September2008InorganicCHEMISTRYInorganicCHEMISTRYAnIndianJournalservedintheregion3430-3350cm-1intheligandsat-tributedtoasymmetricandsymmetricmodesoftheNH2groupremainatnearlythesamepositioninthecom-plexes,indicatingthenon-involvementofthisgroupinchelation.
InadditiontothisthespectrumoftheligandTBDTCZHshowsdoubletat2900and2950cm-1,whichcanbeattributedtosymmetricandasymmetricvibrationsofS-CH2-C6H5grouping16andreducedtoaweakdoubletinthespectraofthecomplexes.
InthespectrumoftheligandTBBZTHtheabsenceof(SH)at2600-2530cm-1and(C=N)at1620-1590cm-1isastrongevidencefortheringstructure.
Oncomplexation,thebandat3240-3150cm-1duetoNHstretchingvibrationsofthebenzothiazoline,disap-pearsandabandat1600cm-1isobserveddueto(C=N)vibrations.
Thechelationofthisbenzothiazolineandthesaidligandsthroughtheazomethinenitrogenandthiolicsulphurfurthergetssupportbytheappear-anceofthenewbandsatca.
650cm-1,435cm-1and360cm-1,inthespectraofthecomplexesdueto(Mo-O),(MoN)and(Mo-S),respectively.
Adoubletinthespectraofthecomplexesatca.
910cm-1,whichmaybeassignedtosym(O=Mo=O)andasy.
(O=Mo=O),respectively,indicatesthecisMoO2struc-ture.
1HNMRspectraThebondingpatterndiscussedabovegetsfurthersupportbytheprotonmagneticresonancespectralstud-iesoftheligandsandtheircomplexes.
The1HNMRspectraoftheligandsTBTSCZH,TBSCZHandTBDTHshowsignalsdueto–NHgroup(10.
65-10.
98ppm)and–SHgroup(7.
88-7.
96ppm).
Incaseofthecorrespondingcomplexthesignalsdueto–NHand–SHprotonsoftheligandunitdisappearindi-catingdeprotonationandsimultaneouscovalentbondformationthroughnitrogenandsulphur.
Allthesaidfreeligandsandtheirmolybdenumcomplexesshowmultip-letsintheregion6.
25-8.
80ppmattributabletoaro-maticprotons,whichappearalmostatthesameposi-tionintherespectiveligands.
TheNH2protonsgivesingletat3.
48-4.
20intheligandsTBTSCZHandTBSCZHaswellastheircorrespondingmolybdenum(VI)complexes.
ItshowsthattheNH2groupisnottakingpartinthecomplexation.
The1HNMRspectrumoftheligandTBBZTHshowsthesignalof–NHprotonat5.
40ppmwhichfoundabsentinthespectraofthemolybdenum(VI)complexesconfirmingthedeprotonationof–NHgroupandcoordinationofmolybdenumwithnitrogenatom.
TheH-C=Nsignalisfoundinupfieldorshieldedre-gioninbenzothiazolineligandanditsmolybdenum(VI)complexesascomparedtothethiosemicarbazone,semicarbazoneanddithiocarbazateandtheirmolybdenum(VI)complexes.
ThespectrumoftheligandTBDTCZHalsoshowsanadditionalpeakat1.
78ppmduetoS-CH2-Phprotonsandthispeakappearsindeshieldregioninitscorrespondingmetalcomplex.
13C-NMRspectraThe13CNMRspectraofoneoftheligandanditscorrespondingmetalcomplexeshavebeenrecordedinCDCl3.
Thechemicalshiftvaluesofthecarbonatomattachedtotheazomethinenitrogen,thiolicsulfuroramidooxygen,showconsiderableshiftwhichfurthersupporttheproposedcoordinationinthecomplexes.
Onthebasisoftheabovestudiesthecoordinationpatternshowninfigure1isconcluded.
AntimicrobialstudiesBioefficiencyoftheparentligandsandtheircom-plexeswastestedinvitroforthegrowthinhibitingpo-tentialagainstvariousfungalandbacterialstrainsusingRadialGrowthMethodandPaperDiscTechnique,re-spectively.
FungalstrainsM.
phaseolina,F.
oxysporumandBacterialstrainsS.
aureusandK.
aerogenous,wereused.
Thebiocidalactivityhavebeencomparedwiththeconventionalfungicide.
Bavistinandtheconven-tionalbactericide,Streptomycin.
AllthescreeningdataaregiveninTABLES3and4.
Itisapparentthatsulfurcontainingcompoundsaremoretoxicthantheoxygencontainingcompounds.
ItXMoXNOONWhere,X=SandOandNXisthedonorsystemoftheligandsFigure1.
192Biologicallypotentdioxomolybdenum(VI)complexesFullPaperICAIJ,3(3)September2008
Alargenum-berofstableandaccessibleoxidationstatesandcoor-dinationnumberrendermolybdenumtobeaversatiletransitionelement.
Molybdenumistheonlyelementinthesecondandthirdtransitionserieswhichplaysmajorroleastraceelementinenzymes.
Thepresenceofcis-dioxymolybdenumcation[MoO2]+2intheoxidizedformofcertainmolybdoenzymeshasrecentlygeneratedtre-AshuChaudhary1*,R.
V.
Singh21DepartmentofChemistry,BanasthaliUniversity,Rajasthan,(INDIA)2DepartmentofChemistry,UniversityofRajasthan,Jaipur-302004,(INDIA)E-mail:ashuchaudhary21@gmail.
comReceived:24thJuly,2008;Accepted:29thJuly,2008mendousinterest[2].
Thecis-[MoO2]+2centredominatesthechemistryofdomolybdenum(VI)complexes[3]andparticipatesinmanyoxygenatomtransferreactions[4-6].
Schiffbasesareanimportantclassofligandsinco-ordinationchemistryandhavemanyapplications[7]invariousfields.
ThechemistryofSchiffbasecomplexescontinuestoattractmanyresearchers[8,9]becauseoftheirwideapplicationsinfoodindustry,dyeindustry,ana-lyticalchemistry,catalysis,antimicrobialactivity,agrochemicalactivity[10]andpharmacologicalapplications[11].
TheSchiffbaseshavebeenfoundtobeactiveagainstdifferenttypesofbacteriaandviruses.
IthasnowbeenobservedthatsomeoftheseshowincreasedKEYWORDSDioxomolybdenum(VI)complexes;Spectralstudies;Schiffbase;Antimicrobialstudies.
ABSTRACTMolybdenum(VI)complexesof3,4,5-trimethoxybenzaldehydethiosemicarbazone(TBTSCZH),3,4,5-trimethoxybenzaldehydesemicarbazone(TBSCZH),3,4,5-trimethoxy-benzaldehydebenzothiazoline(TBBZTH)and3,4,5-trimethoxybenzaldehyde-S-benzyldithiocarbazate(TBDTCZH)havebeensynthesizedandcharacterizedbyphysico-chemicalandspectroscopicstudies.
ThecomplexesMoO2(L)2(whereLrepresentedthedeprotonatedformoftheligands),wereformedbythereactionsbetweendioxobis(2,4-pentanedionato-O,O')molybdenum(VI)andtheligandsTBTSCZH,TBSCZH,TBBZTHandTBDTCZHbyusingbothtechniques(thermalandmicro-wave).
Thestructuralfeaturesofthesemolybdenumcomplexeswereex-ploredbyIR,1HNMR,13CNMRandmolecularweightdeterminations.
Anoctahedralarrangementofligandsaroundthecentralmolybdenumatomisproposed.
Allthefourligandsandtheircomplexeshavebeenscreenedfortheirbiologicalactivityonseveralpathogenicfungiandbacteriaandthedatashowgoodactivityofthesecomplexesandligands.
2008TradeScienceInc.
-INDIAFullPaperICAIJ,3(3),2008[188-192]AnIndianJournalTradeScienceInc.
Volume3Issue3September2008InorganicCHEMISTRYAshuChaudharyandR.
V.
Singh189FullPaperICAIJ,3(3)September2008InorganicCHEMISTRYInorganicCHEMISTRYAnIndianJournalactivitywhenadministeredintheformofazomethinemetalcomplexes[12].
Inviewoftheimportanceofthedioxomolybdenum(VI)complexes,wehavesynthesizedandcharacterizedsomenewcomplexesofthesaidpo-tentialbidentateligands.
EXPERIMENTALAllthechemicalsandsolventsusedweredriedandpurifiedbythestandardmethods.
Dioxobis(2,4-pentanedionato)molybdenum(VI)waspreparedac-cordingtotheliteraturemethod[13].
PreparationoftheLigandsThedifferentrouteswereemployedforthesynthe-sisoftheligands.
Theseare-1.
MicrowaveassistedsynthesisFormicrowaveassistedsynthesisoftheligandsTBTSCZH,TBSCZH,TBBZTHandTBDTCZHthethiosemicarbazide,semicarbazidehydrochloride,2-aminothiophenolandS-benzyldihiocarbazatewerere-actedwith3,4,5-trimethoxybenzaldehydeinethanolicmedia,usingaconventionalmicrowaveoven,wheretheconsumptionofethanolassolventisverylittle(2-3ml).
Thereactionswerecompletedinashortperiod(4-8minutes).
ThecompletionofthereactionischeckedbyTLC.
2.
ConventionalheatingsynthesisForthecomparisonpurpose,aboveligandswerealsosynthesizedbythethermalmethod.
Forthistheweighedamountsof3,4,5-trimethoxybenzaldehydeandthiosemicarbazide,semicarbazidehydrochlorideand2-aminothiophenolandS-benzyldihiocarbazateweremixedtogetherin100mlethanolin250mlbeaker.
Thecontentswererefluxedfor4-16hrs.
onanoilbath.
Thesolidproductswereprecipitated.
Theseweredriedinvacuumandrecrystallizedfromthesamesolvent.
AcomparisonbetweenthermalmethodandmicrowavemethodhasbeengiveninTABLE1.
Theligandsusedare:Preparationofthecomplexes1.
MicrowaveAssistedMethod:Inmicrowaveas-sistedsynthesisthereactionsofdioxobis(2,4-pentanedionato-O,O')molybdenum(VI)withtheligands(TBTSCZH,TBSCZH,TBBZTHandTBDTCZH)werecarriedoutin1:2molarratios,using2-3mlofdrymethanolasasolventusingmi-crowaveoven.
Theproductswererecoveredfromthemicrowaveovenanddriedunderreducedpres-sure.
Theresultingproductswererepeatedlywashedwithdrycyclohexaneandthenfinallydriedat40-60o/0.
5mmfor3-4hours.
2.
ConventionalHeatingMethod:Thesemolybdenum(VI)complexeswerealsosynthesizedbythether-malmethod.
Inthethermalmethodinsteadof4-7minutesreactionswerecompletedin14-16hoursandyieldofproductswerealsolesserthanobtainedbythemicrowaveassistedsynthesis(TABLE1).
RESUTLSANDDISCUSSIONThereactionsofthedioxobis(2,4-pentanedionato-O,O')molybdenum(VI)withthesaidmonofunctionalHCOCH3OCH3OCH3NNHCSNH2HCOCH3OCH3OCH3NNCSHNH2(TBTSCZH)HCOCH3OCH3OCH3NNCOHNH2HCOCH3OCH3OCH3NNHCONH2(TBSCZH)HCOCH3OCH3OCH3NHSHCOCH3OCH3OCH3NHSHCOCH3OCH3OCH3NNHCSSCH2C6H5HCOCH3OCH3OCH3NNCSHSCH2C6H5(TBBZTH)(TBDTCZH).
190Biologicallypotentdioxomolybdenum(VI)complexesFullPaperICAIJ,3(3)September2008AshuChaudharyandR.
V.
Singh191FullPaperICAIJ,3(3)September2008InorganicCHEMISTRYInorganicCHEMISTRYAnIndianJournalservedintheregion3430-3350cm-1intheligandsat-tributedtoasymmetricandsymmetricmodesoftheNH2groupremainatnearlythesamepositioninthecom-plexes,indicatingthenon-involvementofthisgroupinchelation.
InadditiontothisthespectrumoftheligandTBDTCZHshowsdoubletat2900and2950cm-1,whichcanbeattributedtosymmetricandasymmetricvibrationsofS-CH2-C6H5grouping16andreducedtoaweakdoubletinthespectraofthecomplexes.
InthespectrumoftheligandTBBZTHtheabsenceof(SH)at2600-2530cm-1and(C=N)at1620-1590cm-1isastrongevidencefortheringstructure.
Oncomplexation,thebandat3240-3150cm-1duetoNHstretchingvibrationsofthebenzothiazoline,disap-pearsandabandat1600cm-1isobserveddueto(C=N)vibrations.
Thechelationofthisbenzothiazolineandthesaidligandsthroughtheazomethinenitrogenandthiolicsulphurfurthergetssupportbytheappear-anceofthenewbandsatca.
650cm-1,435cm-1and360cm-1,inthespectraofthecomplexesdueto(Mo-O),(MoN)and(Mo-S),respectively.
Adoubletinthespectraofthecomplexesatca.
910cm-1,whichmaybeassignedtosym(O=Mo=O)andasy.
(O=Mo=O),respectively,indicatesthecisMoO2struc-ture.
1HNMRspectraThebondingpatterndiscussedabovegetsfurthersupportbytheprotonmagneticresonancespectralstud-iesoftheligandsandtheircomplexes.
The1HNMRspectraoftheligandsTBTSCZH,TBSCZHandTBDTHshowsignalsdueto–NHgroup(10.
65-10.
98ppm)and–SHgroup(7.
88-7.
96ppm).
Incaseofthecorrespondingcomplexthesignalsdueto–NHand–SHprotonsoftheligandunitdisappearindi-catingdeprotonationandsimultaneouscovalentbondformationthroughnitrogenandsulphur.
Allthesaidfreeligandsandtheirmolybdenumcomplexesshowmultip-letsintheregion6.
25-8.
80ppmattributabletoaro-maticprotons,whichappearalmostatthesameposi-tionintherespectiveligands.
TheNH2protonsgivesingletat3.
48-4.
20intheligandsTBTSCZHandTBSCZHaswellastheircorrespondingmolybdenum(VI)complexes.
ItshowsthattheNH2groupisnottakingpartinthecomplexation.
The1HNMRspectrumoftheligandTBBZTHshowsthesignalof–NHprotonat5.
40ppmwhichfoundabsentinthespectraofthemolybdenum(VI)complexesconfirmingthedeprotonationof–NHgroupandcoordinationofmolybdenumwithnitrogenatom.
TheH-C=Nsignalisfoundinupfieldorshieldedre-gioninbenzothiazolineligandanditsmolybdenum(VI)complexesascomparedtothethiosemicarbazone,semicarbazoneanddithiocarbazateandtheirmolybdenum(VI)complexes.
ThespectrumoftheligandTBDTCZHalsoshowsanadditionalpeakat1.
78ppmduetoS-CH2-Phprotonsandthispeakappearsindeshieldregioninitscorrespondingmetalcomplex.
13C-NMRspectraThe13CNMRspectraofoneoftheligandanditscorrespondingmetalcomplexeshavebeenrecordedinCDCl3.
Thechemicalshiftvaluesofthecarbonatomattachedtotheazomethinenitrogen,thiolicsulfuroramidooxygen,showconsiderableshiftwhichfurthersupporttheproposedcoordinationinthecomplexes.
Onthebasisoftheabovestudiesthecoordinationpatternshowninfigure1isconcluded.
AntimicrobialstudiesBioefficiencyoftheparentligandsandtheircom-plexeswastestedinvitroforthegrowthinhibitingpo-tentialagainstvariousfungalandbacterialstrainsusingRadialGrowthMethodandPaperDiscTechnique,re-spectively.
FungalstrainsM.
phaseolina,F.
oxysporumandBacterialstrainsS.
aureusandK.
aerogenous,wereused.
Thebiocidalactivityhavebeencomparedwiththeconventionalfungicide.
Bavistinandtheconven-tionalbactericide,Streptomycin.
AllthescreeningdataaregiveninTABLES3and4.
Itisapparentthatsulfurcontainingcompoundsaremoretoxicthantheoxygencontainingcompounds.
ItXMoXNOONWhere,X=SandOandNXisthedonorsystemoftheligandsFigure1.
192Biologicallypotentdioxomolybdenum(VI)complexesFullPaperICAIJ,3(3)September2008
- dataavmoo.com相关文档
- roomavmoo.com
- manufacturingavmoo.com
- Hardtopavmoo.com
- 5.avmoo.com
- Guideavmoo.com
- Fitnessavmoo.com
Megalayer(月599元)限时8月香港和美国大带宽服务器
第一、香港服务器机房这里我们可以看到有提供四个大带宽方案，是全向带宽和国际带宽，前者适合除了中国大陆地区的全网地区用户可以用，后者国际带宽适合欧美地区业务。如果我们是需要大陆地区速度CN2优化的，那就需要选择常规的优化带宽方案，参考这里。CPU内存硬盘带宽流量价格选择E3-12308GB240GB SSD50M全向带宽不限999元/月方案选择E3-12308GB240GB SSD100M国际带宽不...
Friendhosting四五折促销,VPS半年付7.5欧元起
Friendhosting发布了针对“系统管理日”(每年7月的最后一个星期五)的优惠活动，针对VPS主机提供55%的优惠(相当于四五折)，支持1-6个月付款使用，首付折扣非永久，优惠后最低套餐首半年7.18欧元起。这是一家保加利亚主机商，成立于2009年4月，商家提供VDS和独立服务器租用等，数据中心目前可选美国洛杉矶、保加利亚、乌克兰、荷兰、拉脱维亚、捷克和波兰等8个地区机房。下面以最低套餐为例...
CloudCone中国新年特别套餐,洛杉矶1G内存VPS年付13.5美元起
CloudCone针对中国农历新年推出了几款特别套餐， 其中2019年前注册的用户可以以13.5美元/年的价格购买一款1G内存特价套餐，以及另外提供了两款不限制注册时间的用户可购买年付套餐。CloudCone是Quadcone旗下成立于2017年的子品牌，提供VPS及独立服务器租用，也是较早提供按小时计费VPS的商家之一，支持使用PayPal或者支付宝等付款方式。下面列出几款特别套餐配置信息。CP...
avmoo.com为你推荐
-
外挂购买外挂什么意思Baby被问婚变绯闻baby的歌词rap那一段为什么不一样微信回应封杀钉钉微信发过来的钉钉链接打不开？留学生认证留学生为什么要做学历认证？关键字编程中，什么是关键字百度关键词价格查询在百度设置关键字是怎么收费的www.haole012.com阜阳有什么好的正规的招聘网站？www.mywife.ccMywife-No 00357 MANAMI SAITO种子下载地址有么？求好心人给www.gogo.comNEO春之色直径？www.99vv1.comwww.in9.com是什么网站啊？