ARe-mail
e-mail 时间:2021-01-11 阅读:()
1MemoryofChiralityinJ-TypeAggregatesofAchiralPeryleneDianhydrideDyeCreatedinaChiralAsymmetricCatalyticSynthesisJin-SongZhao,Yi-BinRuan,RongZhouandYun-BaoJiang*DepartmentofChemistry,CollegeofChemistryandChemicalEngineering,andtheMOEKeyLaboratoryofAnalyticalSciences,XiamenUniversity,Xiamen361005,ChinaE-mail:ybjiang@xmu.
edu.
cnElectronicSupportingInformationTableofcontents1.
Materials,MeasurementsandExperimentalProcedures…22.
ESI-MSofPDAaggregatesdissociatedinDMF(Fig.
S1)33.
AbsorptionandfluorescencespectraofPDAmonomerinDMF(Fig.
S2)44.
AbsorptionandCDspectraofPDAJ-aggregatesmediatedbyL-lacticacid(Fig.
S3)45.
CDspectraofPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofexcessD-tartaricacid(Fig.
S4)56.
1HNMRspectraofPDAJ-aggregatesandofPTKandCTAB(Fig.
S5)57.
1HNMRspectrumofpotassiumL-tartrateinD2O(Fig.
S6)68.
1HNMRspectraofpotassiumtartrateinD2O(Fig.
S7)69.
CDandabsorptionspectraofPDAJ-aggregatesbeforeandafterpurification(Fig.
S8)710.
CDspectraofpurifiedPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofD-tartaricacid(Fig.
S9)711.
XRDofpurifiedPDAJ-andH-aggregates(Fig.
S10)812.
CDandabsorptionspectraofPDAinL-tartaricacid/TTABsolutions(Fig.
S11)813.
References.
921.
Materials,MeasurementsandExperimentalProceduresMaterialsReagentsandsolventswereusedasreceivedfromcommercialsourceswithoutfurtherpurification.
L-(+)-tartaricacid(>99%),D-(-)-tartaricacid(>99%),andperylene-3,4,9,10-tetracarboxylicdianhydride(PDA,>98%)werepurchasedfromAcrosOganics.
Otherchemicals(AR)includingoctadecyltrimthylammoniumbromide(OcTAB),cetyltrimethylammoniumbromide(CTAB),tetradecyltrimethylammoniumbromide(TTAB),decyltrimethylammoniumbromide(DTAB),andHClandKOHwerepurchasedfromGuoyao(Shanghai,China).
Potassiumperylenetetracarboxylate(PTK)wasobtainedfromhydrolysisofPDA.
1Solutionof1.
96g(5mmol)PDAand1.
12g(20mmol)KOHin20mLwaterwasheatedat50°Cfor5hours,duringwhichthedarkredPDApowdergraduallydissolvedtoleadtoadarkredsolution.
Afterfiltration,ethanolwasaddedtothefiltratetoprecipitatePTKthatwasthencollectedthroughfiltrationanddriedundervacuum,affording2.
73gyellowPTKpowderwithayieldof93%.
MeasurementsAbsorptionandCDspectrawererecordedonVarianCary-300UV/VisspectrophotometerandJASCOJ-810spectropolarimeter,respectively.
FluorescencespectrawererecordedonHitachiF-4500fluorescencespectrophotometer.
Electrosprayionizationmassspectrometry(ESI-MS)wasperformedonBrukerESQUIRE-3000plusmassspectrometerbyinjectionofDMFsolutionofthesample.
1HNMRand13CNMRspectrainD2OwererecordedonBrukerAV400spectrometer.
X-raydiffraction(XRD)wasperformedonPanalyticalX'pertPROdiffractometerequippedwithCuKαradiation(λ=1.
5418).
ZetapotentialdatawereobtainedonZetaPALSZetapotentialanalyzer.
Thesemeasurementswerecarriedoutat25°C.
ForCDspectralmeasurements,thesamplesolutioninacellwasstirredbeforethemeasurement.
Thenthesamplewasazimuthallyrotated90oaroundthelightaxisforconsecutivemeasurementsandthusobtainedCDspectrawerefoundtobethesame.
ThereforetheCDsignalsoriginatedexclusivelyfromthemolecularphenomenabutnotfromopticalartifactssuchastheinterferenceoflineardichroism.
2ExperimentalProcedures8mLPTK(62.
5μM)inCTAB(5mM)solutionand2mLL-orD-tartaricacid(2.
5mM,10equiv)inCTAB(5mM)solutionweremixedin10mLflaskat17°C.
Theflaskwassealedandheldat17°Cfor36hours.
Thefinaltransparentsolutionwasinmagenta3colorandwashardlyluminescent.
ThefinalconcentrationofPDAinCTABsolutionwas50μM.
FormationofPDAwasconfirmedbyESI-MS(FigureS1).
PurificationofthesynthesizedchiralPDAJ-aggregateswasperformedusingprecipitationmethod.
Increasingionicstrength,e.
g.
byadditionofsaturatedKBrsolution,resultedinbrownprecipitate.
AfterfiltrationandwashingwithcoldsaturatedKBrsolutionfor3times,theprecipitatewascarefullywashedwithcoldwaterbyavoidingheavystirringanddriedundervacuumbelow15°C.
Theobtaineddarkredprecipitatecanbere-dissolvedinpurewaterunderstirringtoformtransparentmagentasolution.
ConcentrationofthepurifiedPDAJ-aggregatesre-dissolvedinwaterwasmeasuredbyabsorptionspectrophotometry.
3200μLPDAJ-aggregatessolutionwasinjectedinto1.
8mLaqueoussolutionofKOH(1mM)andCTAB(5mM),hydrolysisofPDAtoPTKoccurredimmediatelyandthesolutioncolorturnedtobrightgreen.
Theconcentrationofperylenederivativeswascalculatedbytheabsorbanceat472nmincomparisonwiththestandardworkingcurveoftheabsorbanceat472nmagainstPTKconcentration,independentlypreparedfromabsorptionspectralmeasurementsonstandardPTKsolutions.
2.
ESI-MSofPDAaggregatesdissociatedinDMFESI-MScharacterizationwasperformedinthenegativeionmode.
Samplesolutionwaspreparedbyquickinjectionof40μLPDA(50μM)CTABsolutioninto2mLDMF.
Fig.
S1ESI-MSofPDAmonomerinDMF43.
AbsorptionandfluorescencespectraofPDAmonomerinDMFFig.
S2Normalizedabsorption(solidtrace)andfluorescence(dashtrace,λex=480nm)spectraofPDA(2.
5μM)inDMF.
4.
AbsorptionandCDspectraofPDAJ-aggregatesmediatedbyL-lacticacidFig.
S3(a)CDand(b)absorptionspectraofPDA(50μM)J-aggregatesmediatedbyL-lacticacidinaqueousCTAB(5mM)solution.
55.
CDspectraofPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofexcessD-tartaricacidFig.
S4CDspectrumofthePDA(10μM)J-aggregatesinthepresenceofL-tartaricacid(0.
1mM)(black)andthatoveroneweekafterlateradditionof10-foldexcessofD-tartaricacid(1mM)at10-15°C(red)inaqueousCTABsolutions.
6.
1HNMRspectraofPDAJ-aggregatesandofPTKandCTABFig.
S51HNMRspectraof(a)purifiedPDAJ-aggregatesinD2Oand(b)afterdissociationoftheaggregatesbyaddingexcesssolidKOHinthesameD2Osolution.
SignalsofprotonsinbothPTKandCTABaredistinct,whereasnoC*Hsignaloftartrateat4.
23ppm(Fig.
S6)wasobserved.
TheamountofpossiblyremainingtartaricacidinthepurifiedPDAJ-aggregateswasthereforeestimatedtobemuchlessthan0.
5%ofPDA(Fig.
S7).
67.
1HNMRspectrumofpotassiumL-tartrateinD2OFigS61HNMRspectrumofpotassiumtartrate(20mM)inD2O.
8.
1HNMRspectraofpotassiumtartrateinD2OFig.
S71HNMRspectraof(a)purifiedPDAaggregatesdissociatedbyKOH(portionofFig.
S5b,concentrationoftheformedPTKwasca.
20mM)andpotassiumtartarateatconcentrationof(b)0.
1mM(0.
5%ofPTK),(c)0.
2mM(1%ofPTK)and(d)1mM(5%ofPTK)inthepresenceofPTK(20mM)inD2O.
79.
CDandabsorptionspectraofPDAJ-aggregatesbeforeandafterpurificationFig.
S8(a)CDand(b)absorptionspectraofthePDA(50μM)J-aggregatesmediatedbyL-tartaricacidbefore(blacktrace,inaqueousCTABsolution)andafter(redtrace,inwater)purification.
10.
CDspectraofpurifiedPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofD-tartaricacidFig.
S9CDspectraofpurifiedPDAJ-aggregates(10μM,blacktrace,inwater)mediatedbyL-tartaricacidandthePDAJ-aggregates(10μM)afterlateradditionofD-tartaricacid(1mM,redtrace,inwater).
Thetwotracesarealmostthesame.
811.
XRDofpurifiedPDAJ-andH-aggregatesFig.
S10PowderXRDpatternsofthepurifiedPDA(a)J-and(b)H-aggregates.
TheH-aggregatesderivedfromJ-toH-aggregatestransitioninwaterat30°C.
12.
CDandabsorptionspectraofPDAinL-tartaricacid/TTABsolutionsFig.
S11(a)CDand(b)absorptionspectraofPDA(50μM)inTTABsolutionofvaryingconcentrationinthepresenceof0.
5mML-tartaricacid.
913.
References1(a)W.
L.
Wang,Y.
Bando,C.
Y.
Zhi,W.
Y.
Fu,E.
G.
Wang,D.
Golberg,J.
Am.
Chem.
Soc.
,2008,130,8144-8145;(b)G.
H.
Fu,M.
L.
Wang,Y.
L.
Wang,N.
Xia,X.
J.
Zhang,M.
Yang,P.
Zheng,W.
Wang,C.
Burger,NewJ.
Chem.
,2009,33,784-792.
2(a)C.
Spitz,S.
Dahne,A.
Ouart,H.
W.
Abraham,J.
Phys.
Chem.
B,2000,104,8664-8669;(b)J.
Yuan,M.
H.
Liu,J.
Am.
Chem.
Soc.
,2003,125,5051-5056.
3D.
A.
Skoog,F.
J.
Holler,T.
A.
Nieman,PrinciplesofInstrumentalAnalysis,5thed.
,SaundersCollege,FortWorth,TX,1998,pp.
301-328.
edu.
cnElectronicSupportingInformationTableofcontents1.
Materials,MeasurementsandExperimentalProcedures…22.
ESI-MSofPDAaggregatesdissociatedinDMF(Fig.
S1)33.
AbsorptionandfluorescencespectraofPDAmonomerinDMF(Fig.
S2)44.
AbsorptionandCDspectraofPDAJ-aggregatesmediatedbyL-lacticacid(Fig.
S3)45.
CDspectraofPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofexcessD-tartaricacid(Fig.
S4)56.
1HNMRspectraofPDAJ-aggregatesandofPTKandCTAB(Fig.
S5)57.
1HNMRspectrumofpotassiumL-tartrateinD2O(Fig.
S6)68.
1HNMRspectraofpotassiumtartrateinD2O(Fig.
S7)69.
CDandabsorptionspectraofPDAJ-aggregatesbeforeandafterpurification(Fig.
S8)710.
CDspectraofpurifiedPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofD-tartaricacid(Fig.
S9)711.
XRDofpurifiedPDAJ-andH-aggregates(Fig.
S10)812.
CDandabsorptionspectraofPDAinL-tartaricacid/TTABsolutions(Fig.
S11)813.
References.
921.
Materials,MeasurementsandExperimentalProceduresMaterialsReagentsandsolventswereusedasreceivedfromcommercialsourceswithoutfurtherpurification.
L-(+)-tartaricacid(>99%),D-(-)-tartaricacid(>99%),andperylene-3,4,9,10-tetracarboxylicdianhydride(PDA,>98%)werepurchasedfromAcrosOganics.
Otherchemicals(AR)includingoctadecyltrimthylammoniumbromide(OcTAB),cetyltrimethylammoniumbromide(CTAB),tetradecyltrimethylammoniumbromide(TTAB),decyltrimethylammoniumbromide(DTAB),andHClandKOHwerepurchasedfromGuoyao(Shanghai,China).
Potassiumperylenetetracarboxylate(PTK)wasobtainedfromhydrolysisofPDA.
1Solutionof1.
96g(5mmol)PDAand1.
12g(20mmol)KOHin20mLwaterwasheatedat50°Cfor5hours,duringwhichthedarkredPDApowdergraduallydissolvedtoleadtoadarkredsolution.
Afterfiltration,ethanolwasaddedtothefiltratetoprecipitatePTKthatwasthencollectedthroughfiltrationanddriedundervacuum,affording2.
73gyellowPTKpowderwithayieldof93%.
MeasurementsAbsorptionandCDspectrawererecordedonVarianCary-300UV/VisspectrophotometerandJASCOJ-810spectropolarimeter,respectively.
FluorescencespectrawererecordedonHitachiF-4500fluorescencespectrophotometer.
Electrosprayionizationmassspectrometry(ESI-MS)wasperformedonBrukerESQUIRE-3000plusmassspectrometerbyinjectionofDMFsolutionofthesample.
1HNMRand13CNMRspectrainD2OwererecordedonBrukerAV400spectrometer.
X-raydiffraction(XRD)wasperformedonPanalyticalX'pertPROdiffractometerequippedwithCuKαradiation(λ=1.
5418).
ZetapotentialdatawereobtainedonZetaPALSZetapotentialanalyzer.
Thesemeasurementswerecarriedoutat25°C.
ForCDspectralmeasurements,thesamplesolutioninacellwasstirredbeforethemeasurement.
Thenthesamplewasazimuthallyrotated90oaroundthelightaxisforconsecutivemeasurementsandthusobtainedCDspectrawerefoundtobethesame.
ThereforetheCDsignalsoriginatedexclusivelyfromthemolecularphenomenabutnotfromopticalartifactssuchastheinterferenceoflineardichroism.
2ExperimentalProcedures8mLPTK(62.
5μM)inCTAB(5mM)solutionand2mLL-orD-tartaricacid(2.
5mM,10equiv)inCTAB(5mM)solutionweremixedin10mLflaskat17°C.
Theflaskwassealedandheldat17°Cfor36hours.
Thefinaltransparentsolutionwasinmagenta3colorandwashardlyluminescent.
ThefinalconcentrationofPDAinCTABsolutionwas50μM.
FormationofPDAwasconfirmedbyESI-MS(FigureS1).
PurificationofthesynthesizedchiralPDAJ-aggregateswasperformedusingprecipitationmethod.
Increasingionicstrength,e.
g.
byadditionofsaturatedKBrsolution,resultedinbrownprecipitate.
AfterfiltrationandwashingwithcoldsaturatedKBrsolutionfor3times,theprecipitatewascarefullywashedwithcoldwaterbyavoidingheavystirringanddriedundervacuumbelow15°C.
Theobtaineddarkredprecipitatecanbere-dissolvedinpurewaterunderstirringtoformtransparentmagentasolution.
ConcentrationofthepurifiedPDAJ-aggregatesre-dissolvedinwaterwasmeasuredbyabsorptionspectrophotometry.
3200μLPDAJ-aggregatessolutionwasinjectedinto1.
8mLaqueoussolutionofKOH(1mM)andCTAB(5mM),hydrolysisofPDAtoPTKoccurredimmediatelyandthesolutioncolorturnedtobrightgreen.
Theconcentrationofperylenederivativeswascalculatedbytheabsorbanceat472nmincomparisonwiththestandardworkingcurveoftheabsorbanceat472nmagainstPTKconcentration,independentlypreparedfromabsorptionspectralmeasurementsonstandardPTKsolutions.
2.
ESI-MSofPDAaggregatesdissociatedinDMFESI-MScharacterizationwasperformedinthenegativeionmode.
Samplesolutionwaspreparedbyquickinjectionof40μLPDA(50μM)CTABsolutioninto2mLDMF.
Fig.
S1ESI-MSofPDAmonomerinDMF43.
AbsorptionandfluorescencespectraofPDAmonomerinDMFFig.
S2Normalizedabsorption(solidtrace)andfluorescence(dashtrace,λex=480nm)spectraofPDA(2.
5μM)inDMF.
4.
AbsorptionandCDspectraofPDAJ-aggregatesmediatedbyL-lacticacidFig.
S3(a)CDand(b)absorptionspectraofPDA(50μM)J-aggregatesmediatedbyL-lacticacidinaqueousCTAB(5mM)solution.
55.
CDspectraofPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofexcessD-tartaricacidFig.
S4CDspectrumofthePDA(10μM)J-aggregatesinthepresenceofL-tartaricacid(0.
1mM)(black)andthatoveroneweekafterlateradditionof10-foldexcessofD-tartaricacid(1mM)at10-15°C(red)inaqueousCTABsolutions.
6.
1HNMRspectraofPDAJ-aggregatesandofPTKandCTABFig.
S51HNMRspectraof(a)purifiedPDAJ-aggregatesinD2Oand(b)afterdissociationoftheaggregatesbyaddingexcesssolidKOHinthesameD2Osolution.
SignalsofprotonsinbothPTKandCTABaredistinct,whereasnoC*Hsignaloftartrateat4.
23ppm(Fig.
S6)wasobserved.
TheamountofpossiblyremainingtartaricacidinthepurifiedPDAJ-aggregateswasthereforeestimatedtobemuchlessthan0.
5%ofPDA(Fig.
S7).
67.
1HNMRspectrumofpotassiumL-tartrateinD2OFigS61HNMRspectrumofpotassiumtartrate(20mM)inD2O.
8.
1HNMRspectraofpotassiumtartrateinD2OFig.
S71HNMRspectraof(a)purifiedPDAaggregatesdissociatedbyKOH(portionofFig.
S5b,concentrationoftheformedPTKwasca.
20mM)andpotassiumtartarateatconcentrationof(b)0.
1mM(0.
5%ofPTK),(c)0.
2mM(1%ofPTK)and(d)1mM(5%ofPTK)inthepresenceofPTK(20mM)inD2O.
79.
CDandabsorptionspectraofPDAJ-aggregatesbeforeandafterpurificationFig.
S8(a)CDand(b)absorptionspectraofthePDA(50μM)J-aggregatesmediatedbyL-tartaricacidbefore(blacktrace,inaqueousCTABsolution)andafter(redtrace,inwater)purification.
10.
CDspectraofpurifiedPDAJ-aggregatesmediatedbyL-tartaricacidwithoutandwithlateradditionofD-tartaricacidFig.
S9CDspectraofpurifiedPDAJ-aggregates(10μM,blacktrace,inwater)mediatedbyL-tartaricacidandthePDAJ-aggregates(10μM)afterlateradditionofD-tartaricacid(1mM,redtrace,inwater).
Thetwotracesarealmostthesame.
811.
XRDofpurifiedPDAJ-andH-aggregatesFig.
S10PowderXRDpatternsofthepurifiedPDA(a)J-and(b)H-aggregates.
TheH-aggregatesderivedfromJ-toH-aggregatestransitioninwaterat30°C.
12.
CDandabsorptionspectraofPDAinL-tartaricacid/TTABsolutionsFig.
S11(a)CDand(b)absorptionspectraofPDA(50μM)inTTABsolutionofvaryingconcentrationinthepresenceof0.
5mML-tartaricacid.
913.
References1(a)W.
L.
Wang,Y.
Bando,C.
Y.
Zhi,W.
Y.
Fu,E.
G.
Wang,D.
Golberg,J.
Am.
Chem.
Soc.
,2008,130,8144-8145;(b)G.
H.
Fu,M.
L.
Wang,Y.
L.
Wang,N.
Xia,X.
J.
Zhang,M.
Yang,P.
Zheng,W.
Wang,C.
Burger,NewJ.
Chem.
,2009,33,784-792.
2(a)C.
Spitz,S.
Dahne,A.
Ouart,H.
W.
Abraham,J.
Phys.
Chem.
B,2000,104,8664-8669;(b)J.
Yuan,M.
H.
Liu,J.
Am.
Chem.
Soc.
,2003,125,5051-5056.
3D.
A.
Skoog,F.
J.
Holler,T.
A.
Nieman,PrinciplesofInstrumentalAnalysis,5thed.
,SaundersCollege,FortWorth,TX,1998,pp.
301-328.
百纵科技：美国独立服务器租用/高配置;E52670/32G内存/512G SSD/4IP/50M带宽,999元/月
百纵科技怎么样?百纵科技国人商家,ISP ICP 电信增值许可证的正规公司，近期上线美国C3机房洛杉矶独立服务器，大带宽/高配置多ip站群服务器。百纵科技拥有专业技术售后团队，机器支持自动化，自助安装系统 重启，开机交付时间 30分钟内交付!美国洛杉矶高防服务器配置特点: 硬件配置高 线路稳定 洛杉矶C3机房等级T4 平价销售，支持免费测试，美国独服适合做站，满意付款。点击进入：百纵科技官方网站地...
两款半月湾 HMBcloud 春节88折日本和美国CN2 VPS主机套餐
春节期间我们很多朋友都在忙着吃好喝好，当然有时候也会偶然的上网看看。对于我们站长用户来说，基本上需要等到初八之后才会开工，现在有空就看看是否有商家的促销。这里看到来自HMBcloud半月湾服务商有提供两款春节机房方案的VPS主机88折促销活动，分别是来自洛杉矶CN2 GIA和日本CN2的方案。八八折优惠码：CNY-GIA第一、洛杉矶CN2 GIA美国原生IP地址、72小时退款保障、三网回程CN2 ...
妮妮云香港CTG云服务器1核 1G 3M19元/月
香港ctg云服务器香港ctg云服务器官网链接 点击进入妮妮云官网优惠活动 香港CTG云服务器地区CPU内存硬盘带宽IP价格购买地址香港1核1G20G3M5个19元/月点击购买香港2核2G30G5M10个40元/月点击购买香港2核2G40G5M20个450元/月点击购买香港4核4G50G6M30个80元/月点击购买香...
e-mail为你推荐
-
美国vps服务器美国VPS和美国服务器速度快吗域名备案查询怎么查看域名在什么空间备案的？免备案虚拟空间教你怎么看免备案虚拟主机空间php虚拟空间虚拟空间怎么修改php.ini配置国外网站空间国内空间 美国空间 香港空间相比较,哪个好?独立ip虚拟主机独立ip空间的虚拟主机一般多少钱100m虚拟主机100元虚拟主机山东虚拟主机青岛网络公司哪家好大连虚拟主机大连横展网络科技有限公司怎么样？虚拟主机mysql虚拟主机支持mysql数据库，还需要额外购买mysql吗？